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Memory Disorder

MedGen UID:
7528
•Concept ID:
C0025261
•
Mental or Behavioral Dysfunction
Synonyms: Cognitive Retention Disorder; Cognitive Retention Disorders; Memory Disorders; Retention Disorder, Cognitive; Retention Disorders, Cognitive

Definition

Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions. [from MeSH]

Professional guidelines

PubMed

Pharmacological treatment for memory disorder in multiple sclerosis.
Bellman S
Int J Evid Based Healthc 2017 Dec;15(4):186-187. doi: 10.1097/XEB.0000000000000123. PMID: 28937413
Pharmacological treatment for memory disorder in multiple sclerosis.
He D, Zhang Y, Dong S, Wang D, Gao X, Zhou H
Cochrane Database Syst Rev 2013 Dec 17;(12):CD008876. doi: 10.1002/14651858.CD008876.pub3. PMID: 24343792
Pharmacologic treatment for memory disorder in multiple sclerosis.
He D, Zhou H, Guo D, Hao Z, Wu B
Cochrane Database Syst Rev 2011 Oct 5;(10):CD008876. doi: 10.1002/14651858.CD008876.pub2. PMID: 21975787

Recent clinical studies

Etiology

Factors perpetuating functional cognitive symptoms after mild traumatic brain injury.
Picon EL, Wardell V, Palombo DJ, Todd RM, Aziz B, Bedi S, Silverberg ND
J Clin Exp Neuropsychol 2023 Dec;45(10):988-1002. Epub 2023 Aug 21 doi: 10.1080/13803395.2023.2247601. PMID: 37602857
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ; Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, Van Berckel B, Binette AP, Blennow K, Boada M, Boecker H, Bottlaender M, den Braber A, Brooks DJ, Van Buchem MA, Camus V, Carill JM, Cerman J, Chen K, Chételat G, Chipi E, Cohen AD, Daniels A, Delarue M, Didic M, Drzezga A, Dubois B, Eckerström M, Ekblad LL, Engelborghs S, Epelbaum S, Fagan AM, Fan Y, Fladby T, Fleisher AS, Van der Flier WM, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Frings L, Frisoni GB, Fröhlich L, Gabryelewicz T, Gertz HJ, Gill KD, Gkatzima O, Gómez-Tortosa E, Grimmer T, Guedj E, Habeck CG, Hampel H, Handels R, Hansson O, Hausner L, Hellwig S, Heneka MT, Herukka SK, Hildebrandt H, Hodges J, Hort J, Huang CC, Iriondo AJ, Itoh Y, Ivanoiu A, Jagust WJ, Jessen F, Johannsen P, Johnson KA, Kandimalla R, Kapaki EN, Kern S, Kilander L, Klimkowicz-Mrowiec A, Klunk WE, Koglin N, Kornhuber J, Kramberger MG, Kuo HC, Van Laere K, Landau SM, Landeau B, Lee DY, de Leon M, Leyton CE, Lin KJ, Lleó A, Löwenmark M, Madsen K, Maier W, Marcusson J, Marquié M, Martinez-Lage P, Maserejian N, Mattsson N, de Mendonça A, Meyer PT, Miller BL, Minatani S, Mintun MA, Mok VCT, Molinuevo JL, Morbelli SD, Morris JC, Mroczko B, Na DL, Newberg A, Nobili F, Nordberg A, Olde Rikkert MGM, de Oliveira CR, Olivieri P, Orellana A, Paraskevas G, Parchi P, Pardini M, Parnetti L, Peters O, Poirier J, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Rodríguez-Rodriguez E, Roe CM, Rosa-Neto P, Rosen HJ, Rot U, Rowe CC, Rüther E, Ruiz A, Sabri O, Sakhardande J, Sánchez-Juan P, Sando SB, Santana I, Sarazin M, Scheltens P, Schröder J, Selnes P, Seo SW, Silva D, Skoog I, Snyder PJ, Soininen H, Sollberger M, Sperling RA, Spiru L, Stern Y, Stomrud E, Takeda A, Teichmann M, Teunissen CE, Thompson LI, Tomassen J, Tsolaki M, Vandenberghe R, Verbeek MM, Verhey FRJ, Villemagne V, Villeneuve S, Vogelgsang J, Waldemar G, Wallin A, Wallin ÅK, Wiltfang J, Wolk DA, Yen TC, Zboch M, Zetterberg H
JAMA Neurol 2022 Mar 1;79(3):228-243. doi: 10.1001/jamaneurol.2021.5216. PMID: 35099509
Hippocampal and diencephalic pathology in developmental amnesia.
Dzieciol AM, Bachevalier J, Saleem KS, Gadian DG, Saunders R, Chong WKK, Banks T, Mishkin M, Vargha-Khadem F
Cortex 2017 Jan;86:33-44. Epub 2016 Sep 30 doi: 10.1016/j.cortex.2016.09.016. PMID: 27880886Free PMC Article
Functional (Psychogenic) Cognitive Disorders: A Perspective from the Neurology Clinic.
Stone J, Pal S, Blackburn D, Reuber M, Thekkumpurath P, Carson A
J Alzheimers Dis 2015 Sep 24;48 Suppl 1:S5-S17. doi: 10.3233/JAD-150430. PMID: 26445274
Memory difficulties are not always a sign of incipient dementia: a review of the possible causes of loss of memory efficiency.
Blackburn DJ, Wakefield S, Shanks MF, Harkness K, Reuber M, Venneri A
Br Med Bull 2014 Dec;112(1):71-81. Epub 2014 Oct 1 doi: 10.1093/bmb/ldu029. PMID: 25274571

Diagnosis

Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ; Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, Van Berckel B, Binette AP, Blennow K, Boada M, Boecker H, Bottlaender M, den Braber A, Brooks DJ, Van Buchem MA, Camus V, Carill JM, Cerman J, Chen K, Chételat G, Chipi E, Cohen AD, Daniels A, Delarue M, Didic M, Drzezga A, Dubois B, Eckerström M, Ekblad LL, Engelborghs S, Epelbaum S, Fagan AM, Fan Y, Fladby T, Fleisher AS, Van der Flier WM, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Frings L, Frisoni GB, Fröhlich L, Gabryelewicz T, Gertz HJ, Gill KD, Gkatzima O, Gómez-Tortosa E, Grimmer T, Guedj E, Habeck CG, Hampel H, Handels R, Hansson O, Hausner L, Hellwig S, Heneka MT, Herukka SK, Hildebrandt H, Hodges J, Hort J, Huang CC, Iriondo AJ, Itoh Y, Ivanoiu A, Jagust WJ, Jessen F, Johannsen P, Johnson KA, Kandimalla R, Kapaki EN, Kern S, Kilander L, Klimkowicz-Mrowiec A, Klunk WE, Koglin N, Kornhuber J, Kramberger MG, Kuo HC, Van Laere K, Landau SM, Landeau B, Lee DY, de Leon M, Leyton CE, Lin KJ, Lleó A, Löwenmark M, Madsen K, Maier W, Marcusson J, Marquié M, Martinez-Lage P, Maserejian N, Mattsson N, de Mendonça A, Meyer PT, Miller BL, Minatani S, Mintun MA, Mok VCT, Molinuevo JL, Morbelli SD, Morris JC, Mroczko B, Na DL, Newberg A, Nobili F, Nordberg A, Olde Rikkert MGM, de Oliveira CR, Olivieri P, Orellana A, Paraskevas G, Parchi P, Pardini M, Parnetti L, Peters O, Poirier J, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Rodríguez-Rodriguez E, Roe CM, Rosa-Neto P, Rosen HJ, Rot U, Rowe CC, Rüther E, Ruiz A, Sabri O, Sakhardande J, Sánchez-Juan P, Sando SB, Santana I, Sarazin M, Scheltens P, Schröder J, Selnes P, Seo SW, Silva D, Skoog I, Snyder PJ, Soininen H, Sollberger M, Sperling RA, Spiru L, Stern Y, Stomrud E, Takeda A, Teichmann M, Teunissen CE, Thompson LI, Tomassen J, Tsolaki M, Vandenberghe R, Verbeek MM, Verhey FRJ, Villemagne V, Villeneuve S, Vogelgsang J, Waldemar G, Wallin A, Wallin ÅK, Wiltfang J, Wolk DA, Yen TC, Zboch M, Zetterberg H
JAMA Neurol 2022 Mar 1;79(3):228-243. doi: 10.1001/jamaneurol.2021.5216. PMID: 35099509
Acute amnestic syndromes.
Alessandro L, Ricciardi M, Chaves H, Allegri RF
J Neurol Sci 2020 Jun 15;413:116781. Epub 2020 Mar 18 doi: 10.1016/j.jns.2020.116781. PMID: 32203745
Synaptic Plasticity in PTSD and associated Comorbidities: The Function and Mechanism for Diagnostics and Therapy.
He M, Wei JX, Mao M, Zhao GY, Tang JJ, Feng S, Lu XM, Wang YT
Curr Pharm Des 2018;24(34):4051-4059. doi: 10.2174/1381612824666181120094749. PMID: 30457048
Neuropsychology in a Memory Disorder Clinic.
Ruchinskas RA, Cullum CM
Arch Clin Neuropsychol 2018 May 1;33(3):301-309. doi: 10.1093/arclin/acx128. PMID: 29718078
Neurobehavioral assessment.
Kaufer DI
Continuum (Minneap Minn) 2015 Jun;21(3 Behavioral Neurology and Neuropsychiatry):597-612. doi: 10.1212/01.CON.0000466655.51790.2f. PMID: 26039843

Therapy

Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation for Poststroke Memory Disorder: A Meta-Analysis and Systematic Review.
Xie H, Luo S, Xiong D, Zhu P, Chen J, Tang X, Tan J, Zhao N
J Integr Neurosci 2023 Sep 5;22(5):131. doi: 10.31083/j.jin2205131. PMID: 37735134
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ; Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, Van Berckel B, Binette AP, Blennow K, Boada M, Boecker H, Bottlaender M, den Braber A, Brooks DJ, Van Buchem MA, Camus V, Carill JM, Cerman J, Chen K, Chételat G, Chipi E, Cohen AD, Daniels A, Delarue M, Didic M, Drzezga A, Dubois B, Eckerström M, Ekblad LL, Engelborghs S, Epelbaum S, Fagan AM, Fan Y, Fladby T, Fleisher AS, Van der Flier WM, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Frings L, Frisoni GB, Fröhlich L, Gabryelewicz T, Gertz HJ, Gill KD, Gkatzima O, Gómez-Tortosa E, Grimmer T, Guedj E, Habeck CG, Hampel H, Handels R, Hansson O, Hausner L, Hellwig S, Heneka MT, Herukka SK, Hildebrandt H, Hodges J, Hort J, Huang CC, Iriondo AJ, Itoh Y, Ivanoiu A, Jagust WJ, Jessen F, Johannsen P, Johnson KA, Kandimalla R, Kapaki EN, Kern S, Kilander L, Klimkowicz-Mrowiec A, Klunk WE, Koglin N, Kornhuber J, Kramberger MG, Kuo HC, Van Laere K, Landau SM, Landeau B, Lee DY, de Leon M, Leyton CE, Lin KJ, Lleó A, Löwenmark M, Madsen K, Maier W, Marcusson J, Marquié M, Martinez-Lage P, Maserejian N, Mattsson N, de Mendonça A, Meyer PT, Miller BL, Minatani S, Mintun MA, Mok VCT, Molinuevo JL, Morbelli SD, Morris JC, Mroczko B, Na DL, Newberg A, Nobili F, Nordberg A, Olde Rikkert MGM, de Oliveira CR, Olivieri P, Orellana A, Paraskevas G, Parchi P, Pardini M, Parnetti L, Peters O, Poirier J, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Rodríguez-Rodriguez E, Roe CM, Rosa-Neto P, Rosen HJ, Rot U, Rowe CC, Rüther E, Ruiz A, Sabri O, Sakhardande J, Sánchez-Juan P, Sando SB, Santana I, Sarazin M, Scheltens P, Schröder J, Selnes P, Seo SW, Silva D, Skoog I, Snyder PJ, Soininen H, Sollberger M, Sperling RA, Spiru L, Stern Y, Stomrud E, Takeda A, Teichmann M, Teunissen CE, Thompson LI, Tomassen J, Tsolaki M, Vandenberghe R, Verbeek MM, Verhey FRJ, Villemagne V, Villeneuve S, Vogelgsang J, Waldemar G, Wallin A, Wallin ÅK, Wiltfang J, Wolk DA, Yen TC, Zboch M, Zetterberg H
JAMA Neurol 2022 Mar 1;79(3):228-243. doi: 10.1001/jamaneurol.2021.5216. PMID: 35099509
Apathy as a Treatment Target in Alzheimer's Disease: Implications for Clinical Trials.
Mortby ME, Adler L, Agüera-Ortiz L, Bateman DR, Brodaty H, Cantillon M, Geda YE, Ismail Z, Lanctôt KL, Marshall GA, Padala PR, Politis A, Rosenberg PB, Siarkos K, Sultzer DL, Theleritis C; ISTAART NPS PIA
Am J Geriatr Psychiatry 2022 Feb;30(2):119-147. Epub 2021 Jul 1 doi: 10.1016/j.jagp.2021.06.016. PMID: 34315645
6-Paradol and its glucoside improve memory disorder in mice.
Yamaguchi K , Mitsunaga T , Yamauchi K
Food Funct 2020 Nov 18;11(11):9892-9902. doi: 10.1039/d0fo01975e. PMID: 33094793
Towards universal therapeutics for memory disorders.
Sun MK, Nelson TJ, Alkon DL
Trends Pharmacol Sci 2015 Jun;36(6):384-94. Epub 2015 May 7 doi: 10.1016/j.tips.2015.04.004. PMID: 25959522

Prognosis

The History of Amnesia-a Review.
Langer KG
Curr Neurol Neurosci Rep 2021 Jun 10;21(8):40. doi: 10.1007/s11910-021-01126-x. PMID: 34110519
Effects of aging on action-intentional programming.
Shoraka AR, Otzel DM, M Zilli E, Finney GR, Doty L, Falchook AD, Heilman KM
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 2018 Mar;25(2):244-258. Epub 2017 Mar 6 doi: 10.1080/13825585.2017.1287854. PMID: 28264637
A view of obesity as a learning and memory disorder.
Davidson TL, Tracy AL, Schier LA, Swithers SE
J Exp Psychol Anim Learn Cogn 2014 Jul;40(3):261-79. doi: 10.1037/xan0000029. PMID: 25453037Free PMC Article
Memory difficulties are not always a sign of incipient dementia: a review of the possible causes of loss of memory efficiency.
Blackburn DJ, Wakefield S, Shanks MF, Harkness K, Reuber M, Venneri A
Br Med Bull 2014 Dec;112(1):71-81. Epub 2014 Oct 1 doi: 10.1093/bmb/ldu029. PMID: 25274571
Memory and amnesia.
Mayes AR
Behav Brain Res 1995 Jan 23;66(1-2):29-36. doi: 10.1016/0166-4328(94)00120-5. PMID: 7755895

Clinical prediction guides

Epidemiological and clinical characteristics of survivors of SARS-COV-2 infection: A descriptive study.
Olavegogeascoechea PA, Gallardo Martinez A, Scapellato JL, Federico A
Medwave 2022 Oct 25;22(9):e2581. doi: 10.5867/medwave.2022.09.2581. PMID: 36283026
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ; Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, Van Berckel B, Binette AP, Blennow K, Boada M, Boecker H, Bottlaender M, den Braber A, Brooks DJ, Van Buchem MA, Camus V, Carill JM, Cerman J, Chen K, Chételat G, Chipi E, Cohen AD, Daniels A, Delarue M, Didic M, Drzezga A, Dubois B, Eckerström M, Ekblad LL, Engelborghs S, Epelbaum S, Fagan AM, Fan Y, Fladby T, Fleisher AS, Van der Flier WM, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Frings L, Frisoni GB, Fröhlich L, Gabryelewicz T, Gertz HJ, Gill KD, Gkatzima O, Gómez-Tortosa E, Grimmer T, Guedj E, Habeck CG, Hampel H, Handels R, Hansson O, Hausner L, Hellwig S, Heneka MT, Herukka SK, Hildebrandt H, Hodges J, Hort J, Huang CC, Iriondo AJ, Itoh Y, Ivanoiu A, Jagust WJ, Jessen F, Johannsen P, Johnson KA, Kandimalla R, Kapaki EN, Kern S, Kilander L, Klimkowicz-Mrowiec A, Klunk WE, Koglin N, Kornhuber J, Kramberger MG, Kuo HC, Van Laere K, Landau SM, Landeau B, Lee DY, de Leon M, Leyton CE, Lin KJ, Lleó A, Löwenmark M, Madsen K, Maier W, Marcusson J, Marquié M, Martinez-Lage P, Maserejian N, Mattsson N, de Mendonça A, Meyer PT, Miller BL, Minatani S, Mintun MA, Mok VCT, Molinuevo JL, Morbelli SD, Morris JC, Mroczko B, Na DL, Newberg A, Nobili F, Nordberg A, Olde Rikkert MGM, de Oliveira CR, Olivieri P, Orellana A, Paraskevas G, Parchi P, Pardini M, Parnetti L, Peters O, Poirier J, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Rodríguez-Rodriguez E, Roe CM, Rosa-Neto P, Rosen HJ, Rot U, Rowe CC, Rüther E, Ruiz A, Sabri O, Sakhardande J, Sánchez-Juan P, Sando SB, Santana I, Sarazin M, Scheltens P, Schröder J, Selnes P, Seo SW, Silva D, Skoog I, Snyder PJ, Soininen H, Sollberger M, Sperling RA, Spiru L, Stern Y, Stomrud E, Takeda A, Teichmann M, Teunissen CE, Thompson LI, Tomassen J, Tsolaki M, Vandenberghe R, Verbeek MM, Verhey FRJ, Villemagne V, Villeneuve S, Vogelgsang J, Waldemar G, Wallin A, Wallin ÅK, Wiltfang J, Wolk DA, Yen TC, Zboch M, Zetterberg H
JAMA Neurol 2022 Mar 1;79(3):228-243. doi: 10.1001/jamaneurol.2021.5216. PMID: 35099509
A view of obesity as a learning and memory disorder.
Davidson TL, Tracy AL, Schier LA, Swithers SE
J Exp Psychol Anim Learn Cogn 2014 Jul;40(3):261-79. doi: 10.1037/xan0000029. PMID: 25453037Free PMC Article
Memory difficulties are not always a sign of incipient dementia: a review of the possible causes of loss of memory efficiency.
Blackburn DJ, Wakefield S, Shanks MF, Harkness K, Reuber M, Venneri A
Br Med Bull 2014 Dec;112(1):71-81. Epub 2014 Oct 1 doi: 10.1093/bmb/ldu029. PMID: 25274571
Memory and amnesia.
Mayes AR
Behav Brain Res 1995 Jan 23;66(1-2):29-36. doi: 10.1016/0166-4328(94)00120-5. PMID: 7755895

Recent systematic reviews

Health Information Technology Supporting Adherence Memory Disorder Patients: A Systematic Literature Review.
Elkefi S, Blecker S, Bitan Y
Appl Clin Inform 2024 Jan;15(1):85-100. Epub 2024 Jan 31 doi: 10.1055/s-0043-1776792. PMID: 38295858Free PMC Article
Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation for Poststroke Memory Disorder: A Meta-Analysis and Systematic Review.
Xie H, Luo S, Xiong D, Zhu P, Chen J, Tang X, Tan J, Zhao N
J Integr Neurosci 2023 Sep 5;22(5):131. doi: 10.31083/j.jin2205131. PMID: 37735134
Association between migration and cognitive status among middle-aged and older adults: a systematic review.
Xu H, Zhang Y, Wu B
BMC Geriatr 2017 Aug 17;17(1):184. doi: 10.1186/s12877-017-0585-2. PMID: 28818064Free PMC Article
MIBG myocardial scintigraphy in pre-motor Parkinson's disease: a review.
Sakakibara R, Tateno F, Kishi M, Tsuyusaki Y, Terada H, Inaoka T
Parkinsonism Relat Disord 2014 Mar;20(3):267-73. Epub 2013 Nov 21 doi: 10.1016/j.parkreldis.2013.11.001. PMID: 24332912
Pharmacologic treatment for memory disorder in multiple sclerosis.
He D, Zhou H, Guo D, Hao Z, Wu B
Cochrane Database Syst Rev 2011 Oct 5;(10):CD008876. doi: 10.1002/14651858.CD008876.pub2. PMID: 21975787

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