Neck Squamous Cell Carcinoma of Unknown Primary

MedGen UID:: 65078
•Concept ID:: C0220635
•: Neoplastic Process

Synonyms:

Epidermoid Carcinoma Metastatic to the Neck with Occult Primary; Neck Squamous Cell CUP; Squamous Cell Carcinoma Metastatic in the Neck with Occult Primary; Squamous Cell Carcinoma Metastatic to the Neck with Occult Primary

Definition

A squamous cell carcinoma that has metastasized to the neck region from an unknown primary anatomic site. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVNeck Squamous Cell Carcinoma of Unknown Primary

Neoplasm
- Neoplasm by Special Category
  - Infrequent Neoplasm
    - Cancer of unknown primary site
      - Head and Neck Carcinoma of Unknown Primary
        Neck Carcinoma of Unknown Primary
        Neck Squamous Cell Carcinoma of Unknown Primary
        Recurrent Neck Squamous Cell Carcinoma of Unknown Primary

Professional guidelines

PubMed

Management of unknown primary head and neck cancer with radiation therapy in the era of human papillomavirus (HPV): No longer cutting down the tree to get an apple.

Chen AM
Radiother Oncol 2023 Dec;189:109952. Epub 2023 Oct 14 doi: 10.1016/j.radonc.2023.109952. PMID: 37844736

Clinical practice guidelines for management of head and neck squamous cell carcinoma of unknown primary: an AGREE II appraisal.

Fritz C, Ng JJ, Harris J, Romeo DJ, Prasad A, Moreira A, Rajasekaran K
Eur Arch Otorhinolaryngol 2023 Sep;280(9):4195-4204. Epub 2023 Apr 27 doi: 10.1007/s00405-023-07997-9. PMID: 37103581

Evaluation and management of head and neck squamous cell carcinoma of unknown primary.

Martin JM, Galloway TJ
Surg Oncol Clin N Am 2015 Jul;24(3):579-91. Epub 2015 Apr 11 doi: 10.1016/j.soc.2015.03.007. PMID: 25979401

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