U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Thoracic aortic dissection

MedGen UID:
196449
Concept ID:
C0729233
Disease or Syndrome
Synonyms: Aorta Dissection, Thoracic; Aortic Dissection, Thoracic; Dissection, Thoracic Aorta; Dissection, Thoracic Aortic; Thoracic Aorta Dissection; Thoracic Aorta Dissections; Thoracic Aortic Dissection; Thoracic Aortic Dissections
SNOMED CT: Dissection of thoracic aorta (233994002)

Definition

A tear within the wall of the thoracic aorta. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Thoracic aortic dissection

Professional guidelines

PubMed

Caruana M, Baars MJ, Bashiardes E, Benke K, Björck E, Codreanu A, de Moya Rubio E, Dumfarth J, Evangelista A, Groenink M, Kallenbach K, Kempers M, Keravnou A, Loeys B, Muiño-Mosquera L, Nagy E, Milleron O, Nistri S, Pepe G, Roos-Hesselink J, Szabolcs Z, Teixidó-Tura G, Timmermans J, Van de Laar I, van Kimmenade R, Verstraeten A, Von Kodolitsch Y, De Backer J, Jondeau G
Eur J Med Genet 2023 Jan;66(1):104673. Epub 2022 Nov 29 doi: 10.1016/j.ejmg.2022.104673. PMID: 36460281
Spanos K, Nana P, Behrendt CA, Kouvelos G, Panuccio G, Heidemann F, Matsagkas M, Debus ES, Giannoukas A, Kölbel T
J Endovasc Ther 2021 Apr;28(2):323-331. Epub 2021 Jan 13 doi: 10.1177/1526602820987808. PMID: 33435805
Mokashi SA, Svensson LG
Gen Thorac Cardiovasc Surg 2019 Jan;67(1):59-65. Epub 2017 Oct 13 doi: 10.1007/s11748-017-0831-8. PMID: 29030719

Recent clinical studies

Etiology

Hameed I, Cifu AS, Vallabhajosyula P
JAMA 2023 Mar 7;329(9):756-757. doi: 10.1001/jama.2023.0265. PMID: 36795378
Rylski B, Schilling O, Czerny M
Eur Heart J 2023 Mar 7;44(10):813-821. doi: 10.1093/eurheartj/ehac757. PMID: 36540036
Zhou Z, Cecchi AC, Prakash SK, Milewicz DM
Genes (Basel) 2022 Oct 7;13(10) doi: 10.3390/genes13101814. PMID: 36292699Free PMC Article
Senser EM, Misra S, Henkin S
Cardiol Clin 2021 Nov;39(4):505-515. doi: 10.1016/j.ccl.2021.06.003. PMID: 34686263
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506

Diagnosis

Hameed I, Cifu AS, Vallabhajosyula P
JAMA 2023 Mar 7;329(9):756-757. doi: 10.1001/jama.2023.0265. PMID: 36795378
Rylski B, Schilling O, Czerny M
Eur Heart J 2023 Mar 7;44(10):813-821. doi: 10.1093/eurheartj/ehac757. PMID: 36540036
Caruana M, Baars MJ, Bashiardes E, Benke K, Björck E, Codreanu A, de Moya Rubio E, Dumfarth J, Evangelista A, Groenink M, Kallenbach K, Kempers M, Keravnou A, Loeys B, Muiño-Mosquera L, Nagy E, Milleron O, Nistri S, Pepe G, Roos-Hesselink J, Szabolcs Z, Teixidó-Tura G, Timmermans J, Van de Laar I, van Kimmenade R, Verstraeten A, Von Kodolitsch Y, De Backer J, Jondeau G
Eur J Med Genet 2023 Jan;66(1):104673. Epub 2022 Nov 29 doi: 10.1016/j.ejmg.2022.104673. PMID: 36460281
Senser EM, Misra S, Henkin S
Cardiol Clin 2021 Nov;39(4):505-515. doi: 10.1016/j.ccl.2021.06.003. PMID: 34686263
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506

Therapy

Huang SS, Liu R, Chang S, Li X, Weng X, Ge J
Nutrients 2023 Sep 26;15(19) doi: 10.3390/nu15194150. PMID: 37836434Free PMC Article
Yang M, Zhou X, Pearce SWA, Yang Z, Chen Q, Niu K, Liu C, Luo J, Li D, Shao Y, Zhang C, Chen D, Wu Q, Cutillas PR, Zhao L, Xiao Q, Zhang L
Arterioscler Thromb Vasc Biol 2023 Oct;43(10):1900-1920. Epub 2023 Aug 17 doi: 10.1161/ATVBAHA.123.319281. PMID: 37589142Free PMC Article
Yu H, Jiao X, Yang Y, Lv Q, Du Z, Li L, Hu C, Du Y, Zhang J, Li F, Sun Q, Wang Y, Chen D, Zhang X, Qin Y
Clin Sci (Lond) 2023 Jun 28;137(12):979-993. doi: 10.1042/CS20230031. PMID: 37294581Free PMC Article
Meccanici F, Gökalp AL, Thijssen CGE, Mokhles MM, Bekkers JA, van Kimmenade R, Verhagen HJ, Roos-Hesselink JW, Takkenberg JJM
Interact Cardiovasc Thorac Surg 2022 Mar 31;34(4):616-627. doi: 10.1093/icvts/ivab270. PMID: 34664071Free PMC Article
Takagi H, Umemoto T
Int Angiol 2016 Oct;35(5):433-9. Epub 2015 Jul 29 PMID: 26221978

Prognosis

Salmasi MY, Pirola S, Asimakopoulos G, Nienaber C, Athanasiou T; London Aortic Mechanobiology Working Group
J Thorac Cardiovasc Surg 2023 Oct;166(4):1034-1042. Epub 2022 May 16 doi: 10.1016/j.jtcvs.2022.05.016. PMID: 35672182
Senser EM, Misra S, Henkin S
Cardiol Clin 2021 Nov;39(4):505-515. doi: 10.1016/j.ccl.2021.06.003. PMID: 34686263
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506
Adriaans BP, Wildberger JE, Westenberg JJM, Lamb HJ, Schalla S
Eur Radiol 2019 Dec;29(12):6396-6404. Epub 2019 Jul 5 doi: 10.1007/s00330-019-06320-7. PMID: 31278573Free PMC Article
Shalhub S, Dua A, Brooks J
Semin Vasc Surg 2014 Dec;27(3-4):196-9. Epub 2015 Jan 16 doi: 10.1053/j.semvascsurg.2015.01.001. PMID: 26073830

Clinical prediction guides

Yang M, Zhou X, Pearce SWA, Yang Z, Chen Q, Niu K, Liu C, Luo J, Li D, Shao Y, Zhang C, Chen D, Wu Q, Cutillas PR, Zhao L, Xiao Q, Zhang L
Arterioscler Thromb Vasc Biol 2023 Oct;43(10):1900-1920. Epub 2023 Aug 17 doi: 10.1161/ATVBAHA.123.319281. PMID: 37589142Free PMC Article
Caruana M, Baars MJ, Bashiardes E, Benke K, Björck E, Codreanu A, de Moya Rubio E, Dumfarth J, Evangelista A, Groenink M, Kallenbach K, Kempers M, Keravnou A, Loeys B, Muiño-Mosquera L, Nagy E, Milleron O, Nistri S, Pepe G, Roos-Hesselink J, Szabolcs Z, Teixidó-Tura G, Timmermans J, Van de Laar I, van Kimmenade R, Verstraeten A, Von Kodolitsch Y, De Backer J, Jondeau G
Eur J Med Genet 2023 Jan;66(1):104673. Epub 2022 Nov 29 doi: 10.1016/j.ejmg.2022.104673. PMID: 36460281
Luo BY, Zhou J, Guo D, Yang Q, Tian Q, Cai DP, Zhou RM, Xu ZZ, Wang HJ, Chen SY, Xie WB
Biochim Biophys Acta Mol Basis Dis 2022 Sep 1;1868(9):166447. Epub 2022 May 25 doi: 10.1016/j.bbadis.2022.166447. PMID: 35643386Free PMC Article
Senser EM, Misra S, Henkin S
Cardiol Clin 2021 Nov;39(4):505-515. doi: 10.1016/j.ccl.2021.06.003. PMID: 34686263
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506

Recent systematic reviews

Liu M, Wu X, Wu S, Li X, Xin S, Zhang J
Cardiovasc Intervent Radiol 2023 Oct;46(10):1315-1328. Epub 2023 Sep 8 doi: 10.1007/s00270-023-03537-4. PMID: 37684487
Rai P, Robinson L, Davies HA, Akhtar R, Field M, Madine J
Int J Mol Sci 2022 Aug 16;23(16) doi: 10.3390/ijms23169200. PMID: 36012466Free PMC Article
Li HL, Chan YC, Jia HY, Cheng SW
Ann Vasc Surg 2022 Sep;85:371-382. Epub 2022 Mar 24 doi: 10.1016/j.avsg.2022.03.020. PMID: 35339592
Meccanici F, Gökalp AL, Thijssen CGE, Mokhles MM, Bekkers JA, van Kimmenade R, Verhagen HJ, Roos-Hesselink JW, Takkenberg JJM
Interact Cardiovasc Thorac Surg 2022 Mar 31;34(4):616-627. doi: 10.1093/icvts/ivab270. PMID: 34664071Free PMC Article
Covella M, Milan A, Totaro S, Cuspidi C, Re A, Rabbia F, Veglio F
J Hypertens 2014 Oct;32(10):1928-35; discussion 1935. doi: 10.1097/HJH.0000000000000286. PMID: 24979304

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...