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Hallucinogen dependence, continuous

MedGen UID:
137906
•Concept ID:
C0338749
•
Mental or Behavioral Dysfunction
Synonym: Hallucinogen Dependence, Continuous Use
SNOMED CT: Hallucinogen dependence, continuous (191849000)

Definition

Physical and psychological dependence on hallucinogenics, which is associated with a pattern of continuous use. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHallucinogen dependence, continuous

Professional guidelines

PubMed

The Cannabis-Dependent Relationship Between Methadone Treatment Dose and Illicit Opioid Use in a Community-Based Cohort of People Who Use Drugs.
Lake S, Kerr T, Buxton J, Walsh Z, Cooper ZD, Socías ME, Fairbairn N, Hayashi K, Milloy MJ
Cannabis Cannabinoid Res 2023 Feb;8(1):155-165. Epub 2021 Nov 22 doi: 10.1089/can.2021.0080. PMID: 34813374Free PMC Article
Psychosocial Correlates and Early Substance Abuse Associated With Lifetime Hallucinogen Use Among Hispanic Young Adults.
Yockey A, King K, Vidourek R
Hisp Health Care Int 2020 Mar;18(1):4-11. Epub 2019 Aug 19 doi: 10.1177/1540415319868150. PMID: 31424280
Cannabis for the treatment of ulcerative colitis.
Kafil TS, Nguyen TM, MacDonald JK, Chande N
Cochrane Database Syst Rev 2018 Nov 8;11(11):CD012954. doi: 10.1002/14651858.CD012954.pub2. PMID: 30406638Free PMC Article

Recent clinical studies

Etiology

Cannabis Involvement and Demand in Frequent Concentrate Users Versus Predominantly Flower Users.
Skrzynski CJ, Napolitan A, Hitchcock L, Minhas M, MacKillop J, Bryan AD, Bidwell LC
J Stud Alcohol Drugs 2023 Mar;84(2):214-221. Epub 2022 Oct 14 doi: 10.15288/jsad.22-00066. PMID: 36971716Free PMC Article
Preparedness for healthy ageing and polysubstance use in long-term cannabis users: a population-representative longitudinal study.
Meier MH, Caspi A, Ambler A, Hariri AR, Harrington H, Hogan S, Houts R, Knodt AR, Ramrakha S, Richmond-Rakerd LS, Poulton R, Moffitt TE
Lancet Healthy Longev 2022 Oct;3(10):e703-e714. doi: 10.1016/S2666-7568(22)00201-X. PMID: 36202130Free PMC Article
Adverse effects of psychedelics: From anecdotes and misinformation to systematic science.
Schlag AK, Aday J, Salam I, Neill JC, Nutt DJ
J Psychopharmacol 2022 Mar;36(3):258-272. Epub 2022 Feb 2 doi: 10.1177/02698811211069100. PMID: 35107059Free PMC Article
Possible Consequences of Cannabis Legalization - What Do Research Show?
Žigić N, Hasanović M, Pajević I, Jakovljević M
Psychiatr Danub 2021 Spring-Summer;33(Suppl 4):1184-1195. PMID: 35354186
Pharmacotherapy for pregnant women with addictions.
Rayburn WF, Bogenschutz MP
Am J Obstet Gynecol 2004 Dec;191(6):1885-97. doi: 10.1016/j.ajog.2004.06.082. PMID: 15592269

Diagnosis

Cannabis Involvement and Demand in Frequent Concentrate Users Versus Predominantly Flower Users.
Skrzynski CJ, Napolitan A, Hitchcock L, Minhas M, MacKillop J, Bryan AD, Bidwell LC
J Stud Alcohol Drugs 2023 Mar;84(2):214-221. Epub 2022 Oct 14 doi: 10.15288/jsad.22-00066. PMID: 36971716Free PMC Article
Ibogaine for treating drug dependence. What is a safe dose?
Schep LJ, Slaughter RJ, Galea S, Newcombe D
Drug Alcohol Depend 2016 Sep 1;166:1-5. Epub 2016 Jul 15 doi: 10.1016/j.drugalcdep.2016.07.005. PMID: 27426011
Current approaches and issues in non-clinical evaluation of abuse and dependence.
Moser P, Wolinsky T, Castagné V, Duxon M
J Pharmacol Toxicol Methods 2011 Mar-Apr;63(2):160-7. Epub 2010 Sep 22 doi: 10.1016/j.vascn.2010.09.004. PMID: 20868759
Ecstasy and other club drugs: a review of recent epidemiologic studies.
Leung KS, Cottler LB
Curr Opin Psychiatry 2008 May;21(3):234-41. doi: 10.1097/YCO.0b013e3282f9b1f1. PMID: 18382220
Pharmacotherapy for pregnant women with addictions.
Rayburn WF, Bogenschutz MP
Am J Obstet Gynecol 2004 Dec;191(6):1885-97. doi: 10.1016/j.ajog.2004.06.082. PMID: 15592269

Therapy

Acute effects of intravenous DMT in a randomized placebo-controlled study in healthy participants.
Vogt SB, Ley L, Erne L, Straumann I, Becker AM, Klaiber A, Holze F, Vandersmissen A, Mueller L, Duthaler U, Rudin D, Luethi D, Varghese N, Eckert A, Liechti ME
Transl Psychiatry 2023 May 23;13(1):172. doi: 10.1038/s41398-023-02477-4. PMID: 37221177Free PMC Article
Adverse effects of psychedelics: From anecdotes and misinformation to systematic science.
Schlag AK, Aday J, Salam I, Neill JC, Nutt DJ
J Psychopharmacol 2022 Mar;36(3):258-272. Epub 2022 Feb 2 doi: 10.1177/02698811211069100. PMID: 35107059Free PMC Article
Marijuana Legalization: Impact on Physicians and Public Health.
Wilkinson ST, Yarnell S, Radhakrishnan R, Ball SA, D'Souza DC
Annu Rev Med 2016;67:453-66. Epub 2015 Oct 19 doi: 10.1146/annurev-med-050214-013454. PMID: 26515984Free PMC Article
Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin.
Carhart-Harris RL, Erritzoe D, Williams T, Stone JM, Reed LJ, Colasanti A, Tyacke RJ, Leech R, Malizia AL, Murphy K, Hobden P, Evans J, Feilding A, Wise RG, Nutt DJ
Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2138-43. Epub 2012 Jan 23 doi: 10.1073/pnas.1119598109. PMID: 22308440Free PMC Article
Pharmacotherapy for pregnant women with addictions.
Rayburn WF, Bogenschutz MP
Am J Obstet Gynecol 2004 Dec;191(6):1885-97. doi: 10.1016/j.ajog.2004.06.082. PMID: 15592269

Prognosis

Mood, sleep and pain comorbidity outcomes in cannabis dependent patients: Findings from a nabiximols versus placebo randomised controlled trial.
Montebello M, Jefferies M, Mills L, Bruno R, Copeland J, McGregor I, Rivas C, Jackson MA, Silsbury C, Dunlop A, Lintzeris N; Agonist Replacement For Cannabis Dependence Study Group (ARC-D)
Drug Alcohol Depend 2022 May 1;234:109388. Epub 2022 Mar 3 doi: 10.1016/j.drugalcdep.2022.109388. PMID: 35316689
Cannabinoids in disguise: Δ9-tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles.
Wiley JL, Marusich JA, Lefever TW, Grabenauer M, Moore KN, Thomas BF
Neuropharmacology 2013 Dec;75:145-54. Epub 2013 Aug 2 doi: 10.1016/j.neuropharm.2013.07.022. PMID: 23916483Free PMC Article
Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin.
Carhart-Harris RL, Erritzoe D, Williams T, Stone JM, Reed LJ, Colasanti A, Tyacke RJ, Leech R, Malizia AL, Murphy K, Hobden P, Evans J, Feilding A, Wise RG, Nutt DJ
Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2138-43. Epub 2012 Jan 23 doi: 10.1073/pnas.1119598109. PMID: 22308440Free PMC Article
Current approaches and issues in non-clinical evaluation of abuse and dependence.
Moser P, Wolinsky T, Castagné V, Duxon M
J Pharmacol Toxicol Methods 2011 Mar-Apr;63(2):160-7. Epub 2010 Sep 22 doi: 10.1016/j.vascn.2010.09.004. PMID: 20868759
Pharmacotherapy for pregnant women with addictions.
Rayburn WF, Bogenschutz MP
Am J Obstet Gynecol 2004 Dec;191(6):1885-97. doi: 10.1016/j.ajog.2004.06.082. PMID: 15592269

Clinical prediction guides

Cannabis Involvement and Demand in Frequent Concentrate Users Versus Predominantly Flower Users.
Skrzynski CJ, Napolitan A, Hitchcock L, Minhas M, MacKillop J, Bryan AD, Bidwell LC
J Stud Alcohol Drugs 2023 Mar;84(2):214-221. Epub 2022 Oct 14 doi: 10.15288/jsad.22-00066. PMID: 36971716Free PMC Article
Mood, sleep and pain comorbidity outcomes in cannabis dependent patients: Findings from a nabiximols versus placebo randomised controlled trial.
Montebello M, Jefferies M, Mills L, Bruno R, Copeland J, McGregor I, Rivas C, Jackson MA, Silsbury C, Dunlop A, Lintzeris N; Agonist Replacement For Cannabis Dependence Study Group (ARC-D)
Drug Alcohol Depend 2022 May 1;234:109388. Epub 2022 Mar 3 doi: 10.1016/j.drugalcdep.2022.109388. PMID: 35316689
Adverse effects of psychedelics: From anecdotes and misinformation to systematic science.
Schlag AK, Aday J, Salam I, Neill JC, Nutt DJ
J Psychopharmacol 2022 Mar;36(3):258-272. Epub 2022 Feb 2 doi: 10.1177/02698811211069100. PMID: 35107059Free PMC Article
Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin.
Carhart-Harris RL, Erritzoe D, Williams T, Stone JM, Reed LJ, Colasanti A, Tyacke RJ, Leech R, Malizia AL, Murphy K, Hobden P, Evans J, Feilding A, Wise RG, Nutt DJ
Proc Natl Acad Sci U S A 2012 Feb 7;109(6):2138-43. Epub 2012 Jan 23 doi: 10.1073/pnas.1119598109. PMID: 22308440Free PMC Article
Current approaches and issues in non-clinical evaluation of abuse and dependence.
Moser P, Wolinsky T, Castagné V, Duxon M
J Pharmacol Toxicol Methods 2011 Mar-Apr;63(2):160-7. Epub 2010 Sep 22 doi: 10.1016/j.vascn.2010.09.004. PMID: 20868759

Recent systematic reviews

Cannabis for the treatment of Crohn's disease.
Kafil TS, Nguyen TM, MacDonald JK, Chande N
Cochrane Database Syst Rev 2018 Nov 8;11(11):CD012853. doi: 10.1002/14651858.CD012853.pub2. PMID: 30407616Free PMC Article
Cannabis for the treatment of ulcerative colitis.
Kafil TS, Nguyen TM, MacDonald JK, Chande N
Cochrane Database Syst Rev 2018 Nov 8;11(11):CD012954. doi: 10.1002/14651858.CD012954.pub2. PMID: 30406638Free PMC Article
Pharmacotherapy for pregnant women with addictions.
Rayburn WF, Bogenschutz MP
Am J Obstet Gynecol 2004 Dec;191(6):1885-97. doi: 10.1016/j.ajog.2004.06.082. PMID: 15592269

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