Rapid Hereditary Breast Cancer Test
- GTR Test IDHelpEach Test is a specific, orderable test from a particular laboratory, and is assigned a unique GTR accession number. The format is GTR00000001.1, with a leading prefix 'GTR' followed by 8 digits, a period, then 1 or more digits representing the version. When a laboratory updates a registered test, a new version number is assigned.: GTR000613192.2
- Last updated: 2024-04-15
- Test version history
Clinical testHelpIn the U.S., clinical tests must be performed under CLIA certification. When a lab uses the same methods for a test in both clinical and research settings, the test appears as two separate GTR records. for Breast cancer, susceptibility to
Offered by Mayo Clinic Laboratories
Overview
Test name
HelpThe name the laboratory assigns the test. Used as the default title of the page specific to the test.Rapid Hereditary Breast Cancer Test (BRTP)
This is a clinical test intended for HelpPurposes or indications for the test. Lab-provided.: Diagnosis, Therapeutic management
Click Indication tab for more information.
https://www.mayocliniclabs.com/test-catalog/overview/619957#Specimen
Order URL HelpLink to the laboratory webpage with information about how to order this test. Please note that clicking on this link will open a new tab in your internet browser.: https://www.mayocliniclabs.com/order-tests/index.html
Specimen source
Methodology
HelpThe assay's major method category (biochemical, cytogenetic or molecular genetics); method category (i.e. enzyme assay, chromosome breakage studies, targeted mutation analysis); methodology (i.e. the name of the method used) and instruments used when performing this test.- Molecular Genetics
- CSequence analysis of the entire coding region
- Next-Generation (NGS)/Massively parallel sequencing (MPS)
- Illumina NovaSeq 6000
Establish or confirm diagnosis
- BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer. - PubMed ID: 20301425
- Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. - PubMed ID: 33406487
- https://www.ncbi.nlm.nih.gov/books/NBK1247
Guidance for management
- BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer. - PubMed ID: 20301425
- Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. - PubMed ID: 33406487
- https://www.ncbi.nlm.nih.gov/books/NBK1247
Guidance for selecting a drug therapy and/or dose
- BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer. - PubMed ID: 20301425
- Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. - PubMed ID: 33406487
- https://www.ncbi.nlm.nih.gov/books/NBK1247
Predictive risk information for patient and/or family members
- BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer. - PubMed ID: 20301425
- Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. - PubMed ID: 33406487
- https://www.ncbi.nlm.nih.gov/books/NBK1247
Clinical validity
HelpHow consistently and accurately the test detects or predicts the intermediate or final outcomes of interest. Lab-provided.Not provided
Test services
HelpLaboratory's order or catalog code for the test (used in the order requisition form).- Clinical Testing/Confirmation of Mutations Identified Previously, Order code: FMTT
- NICE, 2023UK NICE Clinical Guideline CG164, Familial breast cancer: classification, care and managing breast cancer and related risks in people with a family history of breast cancer, 2023
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