Genomind Professional PGx Express™
- GTR Test IDHelpEach Test is a specific, orderable test from a particular laboratory, and is assigned a unique GTR accession number. The format is GTR00000001.1, with a leading prefix 'GTR' followed by 8 digits, a period, then 1 or more digits representing the version. When a laboratory updates a registered test, a new version number is assigned.: GTR000523653.8
- Last updated: 2019-10-28
- Test version history
- 523653.13, last updated: 2023-11-21
- 523653.12, last updated: 2022-12-15
- 523653.11, last updated: 2022-01-03
- 523653.10, last updated: 2021-01-21
- 523653.9, last updated: 2020-01-23
- 523653.8, last updated: 2019-10-28
- 523653.7, last updated: 2019-10-23
- 523653.6, last updated: 2019-02-24
- 523653.5, last updated: 2019-02-20
- 523653.4, last updated: 2019-02-19
- 523653.3, last updated: 2019-01-24
- 523653.2, last updated: 2018-02-23
- 523653.1, last updated: 2015-07-06
Clinical testHelpIn the U.S., clinical tests must be performed under CLIA certification. When a lab uses the same methods for a test in both clinical and research settings, the test appears as two separate GTR records. for Major depressive disorder
Offered by Genomind
Overview
Test name
HelpThe name the laboratory assigns the test. Used as the default title of the page specific to the test.Genomind Professional PGx Express™ (GenPro PGx)
This is a clinical test intended for HelpPurposes or indications for the test. Lab-provided.: Drug Response, Therapeutic management
Click Indication tab for more information.
Treating clinicians with prescribing rights may order the test directly from www.genomind.com, by phone at 1-877-895-8658, or by emailing customerservice@genomind.com.
Order URL HelpLink to the laboratory webpage with information about how to order this test. Please note that clicking on this link will open a new tab in your internet browser.: https://genomind.com/how-do-i-get-the-test/
Specimen source
Methodology
HelpThe assay's major method category (biochemical, cytogenetic or molecular genetics); method category (i.e. enzyme assay, chromosome breakage studies, targeted mutation analysis); methodology (i.e. the name of the method used) and instruments used when performing this test.- Molecular Genetics
- DDeletion/duplication analysis
- qPCR
- Other
- TTargeted variant analysis
- SNP Detection
- QuantStudio 12KFLEX Real Time Instrument
- Other
Guidance for management
- Brennan FX, Gardner KR, Lombard J, Perlis RH, et al. A Naturalistic Study of the Effectiveness of Pharmacogenetic Testing to Guide Treatment in Psychiatric Patients With Mood and Anxiety Disorders. Prim Care Companion CNS Disord. 2015; 17 (2). Gardner KR, Brennan FX, Scott R & Lombard J.The potential utility of pharmacogenetic testing in psychiatry. Psychiatry J. 2014;2014:730956. Fagerness J, Fonseca E, Hess GP, Scott R, Gardner KR, et al. Pharmacogenetic-guided psychiatric intervention associated with increased adherence and cost savings. Am J Manag Care. 2014 May;20(5):e146-56.
- https://www.personalizedmedpsych.com/article/S2468-1717(17)30027-3/fulltext
Lifestyle planning
Guidance for selecting a drug therapy and/or dose
- https://www.omicsonline.org/open-access/patient-with-major-depressive-disorder-responds-to-lmethylfolate-postgenetic-testing-2167-1044-3-156.php?aid=24982
- https://www.ncbi.nlm.nih.gov/pubmed/?term=24441311
- https://www.ncbi.nlm.nih.gov/pubmed/?term=24744941
- https://www.ncbi.nlm.nih.gov/pubmed/?term=25916515
Healthcare Cost Savings
Clinical validity
HelpHow consistently and accurately the test detects or predicts the intermediate or final outcomes of interest. Lab-provided.In the field of pharmacogenetics, one aspect of clinical validity is the strength of the association between the genetic variant and the drug outcome in question. The following citations are key studies assessing drug-gene pair associations.
- https://www.ncbi.nlm.nih.gov/pubmed/?term=18982004
- https://www.ncbi.nlm.nih.gov/pubmed/?term=20194480
- https://www.ncbi.nlm.nih.gov/pubmed/?term=21121776
- https://www.ncbi.nlm.nih.gov/pubmed/?term=22137564
- https://www.ncbi.nlm.nih.gov/pubmed/?term=22515274
- https://www.ncbi.nlm.nih.gov/pubmed/?term=23733030
- https://www.ncbi.nlm.nih.gov/pubmed/?term=24034787
- https://www.ncbi.nlm.nih.gov/pubmed/?term=24458010
- https://www.ncbi.nlm.nih.gov/pubmed/?term=24525690
- https://www.ncbi.nlm.nih.gov/pubmed/?term=25231750
- https://www.ncbi.nlm.nih.gov/pubmed/?term=25974703
- https://www.ncbi.nlm.nih.gov/pubmed/?term=27997040
- https://www.ncbi.nlm.nih.gov/pubmed/?term=29282363
- https://www.ncbi.nlm.nih.gov/pubmed/?term=30028366
- https://www.ncbi.nlm.nih.gov/pubmed/?term=30388593
Testing strategy
HelpThe lab's suggested sequence of ordering tests based on clinical scenarios. It may include information on: reflex testing including each test component, and scenarios which prompt additional components of testing; whether lab communicates interim results or automatically proceeds to further analyses; and if any components are performed in another laboratory.Testing of all 24 genes on the panel is done simultaneously. If one gene fails to produce results additional testing is performed where applicable and provider is notified if this will delay the turn-around time of the test. If additional testing cannot be performed due to poor sample quality or insufficient quantity, a sample recollect will be requested. 000 Treating clinicians with prescribing rights may order the test directly from www.genomind.com, by phone at 1-877-895-8658, or by emailing customerservice@genomind.com.
Test services
HelpLaboratory's order or catalog code for the test (used in the order requisition form).- Clinical Testing/Confirmation of Mutations Identified Previously, commentsPharmacogenetic testing
- Custom Deletion/Duplication Testing
- Result interpretation
IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.