SPATA2 spermatogenesis associated 2

Gene ID: 9825, updated on 17-Aug-2024
Gene type: protein coding
Also known as: PD1; tamo; PPP1R145

Summary

Enables signaling receptor complex adaptor activity and ubiquitin-specific protease binding activity. Involved in several processes, including protein deubiquitination; regulation of necroptotic process; and regulation of tumor necrosis factor-mediated signaling pathway. Located in cytoplasm; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Associated conditions

See all available tests in GTR for this gene

Description	Tests
Genome-wide association analysis identifies three psoriasis susceptibility loci. GeneReviews: Not available
Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene. GeneReviews: Not available

Genomic context

Location:: 20q13.13

Sequence:: Chromosome: 20; NC_000020.11 (49903391..49915529, complement)

Total number of exons:: 5

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Variation

Resource	Links for this gene
ClinVar	Variants reported to ClinVar
dbVar	Studies and variants
SNP	Variation Viewer for SPATA2 variants
Genome viewer	Explore NCBI-annotated and select non-NCBI annotated genome assemblies

Links

ClinVar
Related medical variations
dbVar
Link from Gene to dbVar
OMIM
Link to related OMIM entry
PubMed (OMIM)
Gene links to PubMed derived from omim_pubmed_cited links
RefSeq RNAs
Link to Nucleotide RefSeq RNAs
Variation Viewer
Related Variants

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