CREB5 cAMP responsive element binding protein 5
Gene ID: 9586, updated on 28-Oct-2024Gene type: protein coding
Also known as: CREB-5; CREBPA; CRE-BPA
- See all available tests in GTR for this gene
- Go to complete Gene record for CREB5
- Go to Variation Viewer for CREB5 variants
Summary
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genetic Variants Associated with Serum Thyroid Stimulating Hormone (TSH) Levels in European Americans and African Americans from the eMERGE Network. GeneReviews: Not available | |
| Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. GeneReviews: Not available | |
| Genome-wide association study of co-occurring anxiety in major depression. GeneReviews: Not available | |
| Genome-wide meta-analysis for severe diabetic retinopathy. GeneReviews: Not available | |
| Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. GeneReviews: Not available | |
| Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. GeneReviews: Not available |
Genomic context
- Location:
- 7p15.1-p14.3
- Sequence:
- Chromosome: 7; NC_000007.14 (28299321..28825894)
- Total number of exons:
- 19
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for CREB5 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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