PLAA phospholipase A2 activating protein
Gene ID: 9373, updated on 19-Sep-2024Gene type: protein coding
Also known as: DOA1; PLAP; PLA2P; NDMSBA
- See all available tests in GTR for this gene
- Go to complete Gene record for PLAA
- Go to Variation Viewer for PLAA variants
Summary
Predicted to enable ubiquitin binding activity. Involved in cellular response to lipopolysaccharide; macroautophagy; and positive regulation of phospholipase A2 activity. Located in cytoplasm; extracellular exosome; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort. GeneReviews: Not available | |
| Neurodevelopmental disorder with progressive microcephaly, spasticity, and brain anomalies | See labs |
Genomic context
- Location:
- 9p21.2
- Sequence:
- Chromosome: 9; NC_000009.12 (26903372..26947242, complement)
- Total number of exons:
- 15
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for PLAA variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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