LRRFIP1 LRR binding FLII interacting protein 1
Gene ID: 9208, updated on 17-Jun-2024Gene type: protein coding
Also known as: GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1
- See all available tests in GTR for this gene
- Go to complete Gene record for LRRFIP1
- Go to Variation Viewer for LRRFIP1 variants
Summary
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Involved in negative regulation of transcription by RNA polymerase II. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| A variant in the LRRFIP1 gene is associated with adiposity and inflammation. GeneReviews: Not available |
Genomic context
- Location:
- 2q37.3
- Sequence:
- Chromosome: 2; NC_000002.12 (237627587..237781643)
- Total number of exons:
- 26
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for LRRFIP1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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