ZMYM3 zinc finger MYM-type containing 3
Gene ID: 9203, updated on 17-Jun-2024Gene type: protein coding
Also known as: MYM; XFIM; ZNF261; XLID112; DXS6673E; ZNF198L2
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- Go to complete Gene record for ZMYM3
- Go to Variation Viewer for ZMYM3 variants
Summary
This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010]
Associated conditions
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| Description | Tests |
|---|---|
| Intellectual developmental disorder, X-linked 112 | not available |
Copy number response
| Description |
|---|
| Copy number response Haploinsufficency No evidence available (Last evaluated 2012-07-25) ClinGen Genome Curation PageTriplosensitivity No evidence available (Last evaluated 2012-07-25) ClinGen Genome Curation Page |
Genomic context
- Location:
- Xq13.1
- Sequence:
- Chromosome: X; NC_000023.11 (71239624..71255290, complement)
- Total number of exons:
- 28
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for ZMYM3 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
- ZMYM3 @ LOVD
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