MARVELD3 MARVEL domain containing 3
Gene ID: 91862, updated on 14-Nov-2024Gene type: protein coding
Also known as: MARVD3; MRVLDC3
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- Go to complete Gene record for MARVELD3
- Go to Variation Viewer for MARVELD3 variants
Summary
Enables mitogen-activated protein kinase kinase kinase binding activity. Involved in bicellular tight junction assembly. Acts upstream of or within several processes, including negative regulation of JNK cascade; negative regulation of epithelial cell migration; and protein localization to cell junction. Located in bicellular tight junction and cytoplasmic vesicle. [provided by Alliance of Genome Resources, Nov 2024]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genome-wide association study indicates two novel resistance loci for severe malaria. GeneReviews: Not available |
Genomic context
- Location:
- 16q22.2
- Sequence:
- Chromosome: 16; NC_000016.10 (71626184..71641965)
- Total number of exons:
- 5
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for MARVELD3 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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