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EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon

Gene ID: 8893, updated on 2-Nov-2024
Gene type: protein coding
Also known as: CLE; CACH; LVWM; VWM5; EIF-2B; EIF2Bepsilon

Summary

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]

Associated conditions

See all available tests in GTR for this gene

DescriptionTests
A mega-analysis of genome-wide association studies for major depressive disorder.
GeneReviews: Not available
Leukoencephalopathy with vanishing white matter 5not available

Genomic context

Location:
3q27.1
Sequence:
Chromosome: 3; NC_000003.12 (184135358..184145311)
Total number of exons:
17

Links

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