PPP1R1B protein phosphatase 1 regulatory inhibitor subunit 1B
Gene ID: 84152, updated on 2-Nov-2024Gene type: protein coding
Also known as: DARPP32; DARPP-32
- See all available tests in GTR for this gene
- Go to complete Gene record for PPP1R1B
- Go to Variation Viewer for PPP1R1B variants
Summary
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Genomic context
- Location:
- 17q12
- Sequence:
- Chromosome: 17; NC_000017.11 (39626707..39636624)
- Total number of exons:
- 9
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for PPP1R1B variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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