VAV2 vav guanine nucleotide exchange factor 2
Gene ID: 7410, updated on 18-Sep-2024Gene type: protein coding
Also known as: VAV-2
- See all available tests in GTR for this gene
- Go to complete Gene record for VAV2
- Go to Variation Viewer for VAV2 variants
Summary
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels. GeneReviews: Not available | |
| Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis. GeneReviews: Not available | |
| Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. GeneReviews: Not available |
Genomic context
- Location:
- 9q34.2
- Sequence:
- Chromosome: 9; NC_000009.12 (133761894..133992324, complement)
- Total number of exons:
- 32
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for VAV2 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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