TTC1 tetratricopeptide repeat domain 1
Gene ID: 7265, updated on 28-Oct-2024Gene type: protein coding
Also known as: TPR1
- See all available tests in GTR for this gene
- Go to complete Gene record for TTC1
- Go to Variation Viewer for TTC1 variants
Summary
This gene encodes a protein that belongs to the tetratrico peptide repeat superfamily of proteins. The encoded protein plays a role in protein-protein interactions, and binds to the Galpha subunit of G protein-coupled receptors to activate the Ras signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Genomic context
- Location:
- 5q33.3
- Sequence:
- Chromosome: 5; NC_000005.10 (160009139..160065543)
- Total number of exons:
- 8
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for TTC1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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