TRA T cell receptor alpha locus
Gene ID: 6955, updated on 17-Jun-2024Gene type: protein coding
Also known as: IMD7; TCRA; TRA@
Summary
Enables signaling receptor activity. Involved in T cell mediated cytotoxicity directed against tumor cell target and detection of tumor cell. Part of alpha-beta T cell receptor complex. [provided by Alliance of Genome Resources, Apr 2022]
Associated conditions
| Description | Tests |
|---|---|
| A genome-wide association study of recipient genotype and medium-term kidney allograft function. GeneReviews: Not available | |
| Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. GeneReviews: Not available | |
| Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. GeneReviews: Not available | |
| Genome-wide association study and meta-analysis of intraocular pressure. GeneReviews: Not available | |
| Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy. GeneReviews: Not available | |
| Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. GeneReviews: Not available | |
| Narcolepsy is strongly associated with the T-cell receptor alpha locus. GeneReviews: Not available |
Genomic context
- Location:
- 14q11.2
- Sequence:
- Chromosome: 14; NC_000014.9 (21621904..22552132)
- Total number of exons:
- 0
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for TRA variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- IMGT, the international ImMunoGeneTics information system
- Variation ViewerRelated Variants
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