BST1 bone marrow stromal cell antigen 1
Gene ID: 683, updated on 10-Oct-2024Gene type: protein coding
Also known as: CD157; cADPR2
- See all available tests in GTR for this gene
- Go to complete Gene record for BST1
- Go to Variation Viewer for BST1 variants
Summary
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population. GeneReviews: Not available | |
| Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. GeneReviews: Not available | |
| Genome-wide association study of smoking behaviours in patients with COPD. GeneReviews: Not available | |
| Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. GeneReviews: Not available | |
| Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. GeneReviews: Not available | |
| Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. GeneReviews: Not available |
Genomic context
- Location:
- 4p15.32
- Sequence:
- Chromosome: 4; NC_000004.12 (15703065..15774173)
- Total number of exons:
- 15
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for BST1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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