AURKC aurora kinase C
Gene ID: 6795, updated on 12-Sep-2024Gene type: protein coding
Also known as: AIE2; AIK3; ARK3; AurC; SPGF5; STK13; HEL-S-90; aurora-C
- See all available tests in GTR for this gene
- Go to complete Gene record for AURKC
- Go to Variation Viewer for AURKC variants
Summary
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Associated conditions
Genomic context
- Location:
- 19q13.43
- Sequence:
- Chromosome: 19; NC_000019.10 (57231023..57235548)
- Total number of exons:
- 7
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for AURKC variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- AURKC database
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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