SRSF4 serine and arginine rich splicing factor 4
Gene ID: 6429, updated on 3-Nov-2024Gene type: protein coding
Also known as: SFRS4; SRP75
- See all available tests in GTR for this gene
- Go to complete Gene record for SRSF4
- Go to Variation Viewer for SRSF4 variants
Summary
Enables RNA binding activity. Involved in negative regulation of mRNA splicing, via spliceosome. Located in nuclear speck. Biomarker of Down syndrome; acute myeloid leukemia; clear cell renal cell carcinoma; and colon adenocarcinoma. [provided by Alliance of Genome Resources, Nov 2024]
Genomic context
- Location:
- 1p35.3
- Sequence:
- Chromosome: 1; NC_000001.11 (29147743..29181900, complement)
- Total number of exons:
- 10
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for SRSF4 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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