ARHGEF28 Rho guanine nucleotide exchange factor 28

Gene ID: 64283, updated on 3-Nov-2024
Gene type: protein coding
Also known as: RIP2; RGNEF; p190RHOGEF

Summary

This gene encodes a member of the Rho guanine nucleotide exchange factor family. The encoded protein interacts with low molecular weight neurofilament mRNA and may be involved in the formation of amyotrophic lateral sclerosis neurofilament aggregates. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]

Associated conditions

See all available tests in GTR for this gene

Description	Tests
A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis. GeneReviews: Not available
Genetic predictors of fibrin D-dimer levels in healthy adults. GeneReviews: Not available

Genomic context

Location:: 5q13.2

Sequence:: Chromosome: 5; NC_000005.10 (73626196..73941990)

Total number of exons:: 38

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Variation

Resource	Links for this gene
ClinVar	Variants reported to ClinVar
dbVar	Studies and variants
SNP	Variation Viewer for ARHGEF28 variants
Genome viewer	Explore NCBI-annotated and select non-NCBI annotated genome assemblies

Links

ClinVar
Related medical variations
dbVar
Link from Gene to dbVar
OMIM
Link to related OMIM entry
PubMed (OMIM)
Gene links to PubMed derived from omim_pubmed_cited links
RefSeq RNAs
Link to Nucleotide RefSeq RNAs
RefSeqGene
Link to Nucleotide RefSeqGenes
Variation Viewer
Related Variants

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