WDFY1 WD repeat and FYVE domain containing 1
Gene ID: 57590, updated on 6-Oct-2024Gene type: protein coding
Also known as: WDF1; FENS1; FENS-1; ZFYVE17
- See all available tests in GTR for this gene
- Go to complete Gene record for WDFY1
- Go to Variation Viewer for WDFY1 variants
Summary
The protein encoded by this gene is a phosphatidylinositol 3-phosphate binding protein, which contains a FYVE zinc finger domain and multiple WD-40 repeat domains. When exogenously expressed, it localizes to early endosomes. Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain. [provided by RefSeq, Jan 2015]
Genomic context
- Location:
- 2q36.1
- Sequence:
- Chromosome: 2; NC_000002.12 (223875348..223945335, complement)
- Total number of exons:
- 12
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for WDFY1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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