RALGAPA2 Ral GTPase activating protein catalytic subunit alpha 2
Gene ID: 57186, updated on 17-Jun-2024Gene type: protein coding
Also known as: p220; AS250; C20orf74; dJ1049G11; bA287B20.1; dJ1049G11.4
Summary
Predicted to enable GTPase activator activity and protein heterodimerization activity. Predicted to be involved in activation of GTPase activity. Predicted to act upstream of or within Ral protein signal transduction; regulation of exocyst localization; and regulation of protein localization. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Associated conditions
| Description | Tests |
|---|---|
| Heritability and genetic association analysis of cognition in the Diabetes Heart Study. GeneReviews: Not available | |
| Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. GeneReviews: Not available |
Genomic context
- Location:
- 20p11.23
- Sequence:
- Chromosome: 20; NC_000020.11 (20389530..20712644, complement)
- Total number of exons:
- 48
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for RALGAPA2 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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