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CHMP1B charged multivesicular body protein 1B

Gene ID: 57132, updated on 28-Oct-2024
Gene type: protein coding
Also known as: Vps46B; C10orf2; C18orf2; CHMP1.5; Vps46-2; C18-ORF2; hVps46-2

Summary

CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]

Associated conditions

See all available tests in GTR for this gene

DescriptionTests
Genome-wide association study of exercise behavior in Dutch and American adults.
GeneReviews: Not available

Genomic context

Location:
18p11.21
Sequence:
Chromosome: 18; NC_000018.10 (11851413..11854444)
Total number of exons:
1

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