SPIRE1 spire type actin nucleation factor 1
Gene ID: 56907, updated on 2-Nov-2024Gene type: protein coding
Also known as: Spir-1
- See all available tests in GTR for this gene
- Go to complete Gene record for SPIRE1
- Go to Variation Viewer for SPIRE1 variants
Summary
Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]).[supplied by OMIM, Mar 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genome-wide association study of antibody response to smallpox vaccine. GeneReviews: Not available |
Genomic context
- Location:
- 18p11.21
- Sequence:
- Chromosome: 18; NC_000018.10 (12446512..12662091, complement)
- Total number of exons:
- 26
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for SPIRE1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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