ATF7IP activating transcription factor 7 interacting protein
Gene ID: 55729, updated on 2-Nov-2024Gene type: protein coding
Also known as: AM; MCAF; p621; MCAF1; ATF-IP; ATF7IP1
- See all available tests in GTR for this gene
- Go to complete Gene record for ATF7IP
- Go to Variation Viewer for ATF7IP variants
Summary
ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA. GeneReviews: Not available | |
| Genome-wide association study of breast cancer in the Japanese population. GeneReviews: Not available | |
| Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14. GeneReviews: Not available | |
| Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer. GeneReviews: Not available |
Genomic context
- Location:
- 12p13.1
- Sequence:
- Chromosome: 12; NC_000012.12 (14365682..14502930)
- Total number of exons:
- 22
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for ATF7IP variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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