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ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

Gene ID: 55616, updated on 28-Oct-2024
Gene type: protein coding
Also known as: ACAP4; UPLC1; CENTB6; DDEFL1

Summary

This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

Associated conditions

See all available tests in GTR for this gene

DescriptionTests
Discovery and refinement of loci associated with lipid levels.
GeneReviews: Not available

Genomic context

Location:
1p36.12
Sequence:
Chromosome: 1; NC_000001.11 (23428563..23484631, complement)
Total number of exons:
26

Links

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