RNPC3 RNA binding region (RNP1, RRM) containing 3
Gene ID: 55599, updated on 17-Sep-2024Gene type: protein coding
Also known as: RNP; CPHD7; IGHD5; RBM40; SNRNP65
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- Go to complete Gene record for RNPC3
- Go to Variation Viewer for RNPC3 variants
Summary
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008]
Associated conditions
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Description | Tests |
---|---|
Isolated growth hormone deficiency, type 5 | See labs |
Genomic context
- Location:
- 1p21.1
- Sequence:
- Chromosome: 1; NC_000001.11 (103525699..103555239)
- Total number of exons:
- 15
Variation
Resource | Links for this gene |
---|---|
ClinVar | Variants reported to ClinVar |
dbVar | Studies and variants |
SNP | Variation Viewer for RNPC3 variants |
Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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