TRPM4 transient receptor potential cation channel subfamily M member 4

Gene ID: 54795, updated on 28-Oct-2024
Gene type: protein coding
Also known as: EKVP6; LTrpC4; PFHB1B; TRPM4B; hTRPM4

Summary

The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport calcium. [provided by RefSeq, Mar 2016]

Associated conditions

See all available tests in GTR for this gene

Description	Tests
Erythrokeratodermia variabilis et progressiva 6 MedGen: C5193144OMIM: 618531GeneReviews: Not available	See labs
Progressive familial heart block type IB MedGen: C1970298OMIM: 604559GeneReviews: Not available	See labs

Genomic context

Location:: 19q13.33

Sequence:: Chromosome: 19; NC_000019.10 (49157792..49211836)

Total number of exons:: 25

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Variation

Resource	Links for this gene
ClinVar	Variants reported to ClinVar
dbVar	Studies and variants
SNP	Variation Viewer for TRPM4 variants
Genome viewer	Explore NCBI-annotated and select non-NCBI annotated genome assemblies

Links

ClinVar
Related medical variations
dbVar
Link from Gene to dbVar
MedGen
Related information in MedGen
OMIM
Link to related OMIM entry
PubMed (OMIM)
Gene links to PubMed derived from omim_pubmed_cited links
RefSeq RNAs
Link to Nucleotide RefSeq RNAs
RefSeqGene
Link to Nucleotide RefSeqGenes
TRPM4 database
Variation Viewer
Related Variants

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