POU3F3 POU class 3 homeobox 3
Gene ID: 5455, updated on 28-Sep-2024Gene type: protein coding
Also known as: BRN1; OTF8; oct-8; SNIBFIS; brain-1
- See all available tests in GTR for this gene
- Go to complete Gene record for POU3F3
- Go to Variation Viewer for POU3F3 variants
Summary
This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by RefSeq, Apr 2015]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genetic association with overall survival of taxane-treated lung cancer patients - A genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study. GeneReviews: Not available | |
| Snijders blok-fisher syndrome | not available |
Genomic context
- Location:
- 2q12.1
- Sequence:
- Chromosome: 2; NC_000002.12 (104854115..104858574)
- Total number of exons:
- 1
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for POU3F3 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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