KCNK10 potassium two pore domain channel subfamily K member 10
Gene ID: 54207, updated on 2-Nov-2024Gene type: protein coding
Also known as: TREK2; TREK-2; K2p10.1; PPP1R97
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- Go to complete Gene record for KCNK10
- Go to Variation Viewer for KCNK10 variants
Summary
The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genome-wide genetic and transcriptomic investigation of variation in antibody response to dietary antigens. GeneReviews: Not available |
Genomic context
- Location:
- 14q31.3
- Sequence:
- Chromosome: 14; NC_000014.9 (88180108..88326912, complement)
- Total number of exons:
- 9
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for KCNK10 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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