PLP2 proteolipid protein 2
Gene ID: 5355, updated on 2-Nov-2024Gene type: protein coding
Also known as: A4; A4LSB
Summary
This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked cognitive disability. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010]
Genomic context
- Location:
- Xp11.23
- Sequence:
- Chromosome: X; NC_000023.11 (49171898..49175235)
- Total number of exons:
- 5
Variation
| Resource | Links for this gene |
|---|---|
| SNP | Variation Viewer for PLP2 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
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