ARID4B AT-rich interaction domain 4B
Gene ID: 51742, updated on 19-Sep-2024Gene type: protein coding
Also known as: BCAA; BRCAA1; RBP1L1; SAP180; RBBP1L1
- See all available tests in GTR for this gene
- Go to complete Gene record for ARID4B
- Go to Variation Viewer for ARID4B variants
Summary
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
Genomic context
- Location:
- 1q42.3
- Sequence:
- Chromosome: 1; NC_000001.11 (235166902..235328179, complement)
- Total number of exons:
- 28
Variation
Resource | Links for this gene |
---|---|
ClinVar | Variants reported to ClinVar |
dbVar | Studies and variants |
SNP | Variation Viewer for ARID4B variants |
Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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