DBR1 debranching RNA lariats 1

Gene ID: 51163, updated on 6-Oct-2024
Gene type: protein coding
Also known as: XGIP

Summary

The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2'-5' prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication. [provided by RefSeq, Nov 2011]

Associated conditions

See all available tests in GTR for this gene

Description	Tests
Encephalitis, acute, infection (viral)-induced, susceptibility to, 11 MedGen: C5561941OMIM: 619441GeneReviews: Not available	See labs
Xerosis and growth failure with immune and pulmonary dysfunction syndrome MedGen: C5882692OMIM: 620510GeneReviews: Not available	not available

Genomic context

Location:: 3q22.3

Sequence:: Chromosome: 3; NC_000003.12 (138160988..138174921, complement)

Total number of exons:: 8

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Variation

Resource	Links for this gene
ClinVar	Variants reported to ClinVar
dbVar	Studies and variants
SNP	Variation Viewer for DBR1 variants
Genome viewer	Explore NCBI-annotated and select non-NCBI annotated genome assemblies

Links

ClinVar
Related medical variations
dbVar
Link from Gene to dbVar
MedGen
Related information in MedGen
OMIM
Link to related OMIM entry
PubMed (OMIM)
Gene links to PubMed derived from omim_pubmed_cited links
RefSeq RNAs
Link to Nucleotide RefSeq RNAs
Variation Viewer
Related Variants

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