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ORC5 origin recognition complex subunit 5

Gene ID: 5001, updated on 14-Nov-2024
Gene type: protein coding
Also known as: ORC5L; ORC5P; ORC5T; PPP1R117

Summary

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Oct 2010]

Genomic context

Location:
7q22.1-q22.2
Sequence:
Chromosome: 7; NC_000007.14 (104126341..104208013, complement)
Total number of exons:
15

Links

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