ATP4A ATPase H+/K+ transporting subunit alpha
Gene ID: 495, updated on 2-Nov-2024Gene type: protein coding
Also known as: ATP6A
Summary
The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]
Genomic context
- Location:
- 19q13.12
- Sequence:
- Chromosome: 19; NC_000019.10 (35550031..35563658, complement)
- Total number of exons:
- 22
Variation
| Resource | Links for this gene |
|---|---|
| SNP | Variation Viewer for ATP4A variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
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