KPNA4 karyopherin subunit alpha 4
Gene ID: 3840, updated on 17-Aug-2024Gene type: protein coding
Also known as: QIP1; SRP3; IPOA3
Summary
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008]
Associated conditions
| Description | Tests |
|---|---|
| Genome-Wide Association Study of Primary Dentition Pit-and-Fissure and Smooth Surface Caries. GeneReviews: Not available |
Genomic context
- Location:
- 3q25.33
- Sequence:
- Chromosome: 3; NC_000003.12 (160495007..160565571, complement)
- Total number of exons:
- 17
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for KPNA4 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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