KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1
Gene ID: 3779, updated on 28-Oct-2024Gene type: protein coding
Also known as: hbeta1; BKbeta1; SLO-BETA; hslo-beta; K(VCA)beta; slo-beta-1; k(VCA)beta-1
Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. [provided by RefSeq, Jul 2008]
Associated conditions
| Description | Tests |
|---|---|
| Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. GeneReviews: Not available | |
| Hypertension, diastolic, resistance to | not available |
Genomic context
- Location:
- 5q35.1
- Sequence:
- Chromosome: 5; NC_000005.10 (170374671..170389367, complement)
- Total number of exons:
- 4
Variation
| Resource | Links for this gene |
|---|---|
| SNP | Variation Viewer for KCNMB1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
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