ITGA9 integrin subunit alpha 9
Gene ID: 3680, updated on 17-Jun-2024Gene type: protein coding
Also known as: RLC; ITGA4L; ALPHA-RLC
- See all available tests in GTR for this gene
- Go to complete Gene record for ITGA9
- Go to Variation Viewer for ITGA9 variants
Summary
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma. GeneReviews: Not available | |
| A genome-wide association study of behavioral disinhibition. GeneReviews: Not available | |
| Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations. GeneReviews: Not available | |
| Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. GeneReviews: Not available | |
| Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. GeneReviews: Not available |
Genomic context
- Location:
- 3p22.2
- Sequence:
- Chromosome: 3; NC_000003.12 (37452141..37823507)
- Total number of exons:
- 28
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for ITGA9 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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