CCN1 cellular communication network factor 1
Gene ID: 3491, updated on 27-Aug-2024Gene type: protein coding
Also known as: GIG1; CYR61; IGFBP10
- See all available tests in GTR for this gene
- Go to complete Gene record for CCN1
- Go to Variation Viewer for CCN1 variants
Summary
The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011]
Genomic context
- Location:
- 1p22.3
- Sequence:
- Chromosome: 1; NC_000001.11 (85580761..85583950)
- Total number of exons:
- 5
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for CCN1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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