HES1 hes family bHLH transcription factor 1
Gene ID: 3280, updated on 27-Aug-2024Gene type: protein coding
Also known as: HHL; HRY; HES-1; bHLHb39
- See all available tests in GTR for this gene
- Go to complete Gene record for HES1
- Go to Variation Viewer for HES1 variants
Summary
This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. [provided by RefSeq, Jul 2008]
Genomic context
- Location:
- 3q29
- Sequence:
- Chromosome: 3; NC_000003.12 (194136148..194138732)
- Total number of exons:
- 4
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for HES1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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