HK2 hexokinase 2
Gene ID: 3099, updated on 10-Oct-2024Gene type: protein coding
Also known as: HKII; HXK2
- See all available tests in GTR for this gene
- Go to complete Gene record for HK2
- Go to Variation Viewer for HK2 variants
Summary
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Bivariate genome-wide association analyses of femoral neck bone geometry and appendicular lean mass. GeneReviews: Not available |
Genomic context
- Location:
- 2p12
- Sequence:
- Chromosome: 2; NC_000002.12 (74834127..74893359)
- Total number of exons:
- 20
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for HK2 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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