TNRC6A trinucleotide repeat containing adaptor 6A
Gene ID: 27327, updated on 17-Aug-2024Gene type: protein coding
Also known as: GW1; FAME6; GW182; TNRC6; CAGH26
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- Go to complete Gene record for TNRC6A
- Go to Variation Viewer for TNRC6A variants
Summary
This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
Description | Tests |
---|---|
Epilepsy, familial adult myoclonic, 6 | See labs |
Exploring genome-wide - dietary heme iron intake interactions and the risk of type 2 diabetes. GeneReviews: Not available |
Genomic context
- Location:
- 16p12.1
- Sequence:
- Chromosome: 16; NC_000016.10 (24610205..24826218)
- Total number of exons:
- 28
Variation
Resource | Links for this gene |
---|---|
ClinVar | Variants reported to ClinVar |
dbVar | Studies and variants |
SNP | Variation Viewer for TNRC6A variants |
Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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