ADGRA2 adhesion G protein-coupled receptor A2
Gene ID: 25960, updated on 2-Nov-2024Gene type: protein coding
Also known as: TEM5; GPR124
- See all available tests in GTR for this gene
- Go to complete Gene record for ADGRA2
- Go to Variation Viewer for ADGRA2 variants
Summary
Predicted to enable G protein-coupled receptor activity. Involved in canonical Wnt signaling pathway. Located in intracellular membrane-bounded organelle and plasma membrane. Part of Wnt signalosome. [provided by Alliance of Genome Resources, Nov 2024]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Loci at chromosomes 13, 19 and 20 influence age at natural menopause. GeneReviews: Not available | |
| Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. GeneReviews: Not available |
Genomic context
- Location:
- 8p11.23
- Sequence:
- Chromosome: 8; NC_000008.11 (37796883..37844896)
- Total number of exons:
- 19
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for ADGRA2 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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