LRRC8B leucine rich repeat containing 8 VRAC subunit B
Gene ID: 23507, updated on 19-Sep-2024Gene type: protein coding
Also known as: TALRRP; TA-LRRP
- See all available tests in GTR for this gene
- Go to complete Gene record for LRRC8B
- Go to Variation Viewer for LRRC8B variants
Summary
Contributes to volume-sensitive anion channel activity. Involved in anion transmembrane transport. Located in cytoplasm and plasma membrane. Is integral component of plasma membrane. Part of ion channel complex. [provided by Alliance of Genome Resources, Apr 2022]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. GeneReviews: Not available |
Genomic context
- Location:
- 1p22.2
- Sequence:
- Chromosome: 1; NC_000001.11 (89524829..89597861)
- Total number of exons:
- 9
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for LRRC8B variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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