ADGRL2 adhesion G protein-coupled receptor L2
Gene ID: 23266, updated on 10-Oct-2024Gene type: protein coding
Also known as: CL2; LEC1; CIRL2; LPHH1; LPHN2
- See all available tests in GTR for this gene
- Go to complete Gene record for ADGRL2
- Go to Variation Viewer for ADGRL2 variants
Summary
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Associated conditions
See all available tests in GTR for this gene
Description | Tests |
---|---|
A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. GeneReviews: Not available | |
Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. GeneReviews: Not available | |
UGT1A1 is a major locus influencing bilirubin levels in African Americans. GeneReviews: Not available |
Genomic context
- Location:
- 1p31.1
- Sequence:
- Chromosome: 1; NC_000001.11 (81306132..81993932)
- Total number of exons:
- 41
Variation
Resource | Links for this gene |
---|---|
ClinVar | Variants reported to ClinVar |
dbVar | Studies and variants |
SNP | Variation Viewer for ADGRL2 variants |
Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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