HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Gene ID: 23072, updated on 27-Aug-2024Gene type: protein coding
Also known as: NEDL1
- See all available tests in GTR for this gene
- Go to complete Gene record for HECW1
- Go to Variation Viewer for HECW1 variants
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of sodium ion transmembrane transporter activity; and regulation of dendrite morphogenesis. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus. GeneReviews: Not available | |
| Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. GeneReviews: Not available | |
| Meta-analysis of genome-wide association studies in african americans provides insights into the genetic architecture of type 2 diabetes. GeneReviews: Not available | |
| Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. GeneReviews: Not available |
Genomic context
- Location:
- 7p14.1-p13
- Sequence:
- Chromosome: 7; NC_000007.14 (43112647..43566001)
- Total number of exons:
- 35
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for HECW1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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