DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
Gene ID: 22894, updated on 6-Oct-2024Gene type: protein coding
Also known as: RRP44; dis3p; EXOSC11; KIAA1008; 2810028N01Rik
- See all available tests in GTR for this gene
- Go to complete Gene record for DIS3
- Go to Variation Viewer for DIS3 variants
Summary
Enables 3'-5'-exoribonuclease activity; endonuclease activity; and guanyl-nucleotide exchange factor activity. Involved in CUT catabolic process and rRNA catabolic process. Located in cytosol and nucleoplasm. Part of nuclear exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022]
Genomic context
- Location:
- 13q21.33
- Sequence:
- Chromosome: 13; NC_000013.11 (72752169..72781900, complement)
- Total number of exons:
- 22
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for DIS3 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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