KIF6 kinesin family member 6
Gene ID: 221458, updated on 17-Jun-2024Gene type: protein coding
Also known as: C6orf102; dJ137F1.4; dJ188D3.1; dJ1043E3.1
- See all available tests in GTR for this gene
- Go to complete Gene record for KIF6
- Go to Variation Viewer for KIF6 variants
Summary
This gene encodes a member of a family of molecular motors which are involved in intracellular transport of protein complexes, membrane organelles, and messenger ribonucleic acid along microtubules. Kinesins function as homodimeric molecules with two N-terminal head domains that move along microtubules and two C-terminal tail domains that interact with the transported cargo, either directly or indirectly, through adapter molecules. This gene is ubiquitously expressed in coronary arteries and other vascular tissue. A naturally occurring mutation in this gene is associated with coronary heart disease. [provided by RefSeq, May 2017]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan. GeneReviews: Not available | |
| Genome-wide association study of antibody response to smallpox vaccine. GeneReviews: Not available | |
| Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries. GeneReviews: Not available | |
| Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. GeneReviews: Not available |
Genomic context
- Location:
- 6p21.2
- Sequence:
- Chromosome: 6; NC_000006.12 (39329990..39725408, complement)
- Total number of exons:
- 26
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for KIF6 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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