ACSL1 acyl-CoA synthetase long chain family member 1
Gene ID: 2180, updated on 10-Oct-2024Gene type: protein coding
Also known as: ACS1; LACS; FACL1; FACL2; LACS1; LACS2
- See all available tests in GTR for this gene
- Go to complete Gene record for ACSL1
- Go to Variation Viewer for ACSL1 variants
Summary
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Genomic context
- Location:
- 4q35.1
- Sequence:
- Chromosome: 4; NC_000004.12 (184755595..184826594, complement)
- Total number of exons:
- 31
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for ACSL1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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